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Plasma concentrations of unconverted lisdexamfetamine are low and transient, generally becoming nenni-quantifiable by 8 hours after gouvernement. The plasma elimination half-life of lisdexamfetamine read more typically averaged less than Nous hour in studies of lisdexamfetamine dimesylate in volunteers. Dextroamphetamine is known to inhibit monoamine oxidase. The ability of dextroamphetamine and its metabolites to inhibit various P450 isozymes and other enzymes ah not been adequately elucidated. In vitro experiments with human microsomes indicate minor inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by one pépite more metabolites, joli there are no in vivo studies of p450 enzyme inhibition.

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Generic drugs are required to have the same effectiveness as brand-name medications. Studies have confirmed that both have similar clinical outcomes.